- Blinky- He is main character and an everyman despite being a rabbit. He is often bitter and depressed. He usually has a dead end job and embodies alienation and dread. He often sees a therapist and has a bad apartment. Despite this, he usually is full of wise sayings.
- Sheba- Blinky's girlfriend. She and Blinky are often used a generic couple when the plot demands one.
- Bongo- He is Blinky's one eared illegitimate son. Matt has made several references to him in cartoons he works on.
- Akbar & Jeff- Two "brothers or lovers... and possibly both". Matt claims they are gay. They have Charlie Brown-like shirts and fezzes and own many businesses such as Akabr & Jeff's Bootleg "Akbar & Jeff" T-Shirt Hut. They some time appear in 16-panel grid strips that only they appear in. Unlike most of the characters, they are human.
- Matt Groening and his sons sometime appear as rabbits.
- Snarla- A cat that looks like Lisa Simpson. She is Bongo's love interest and classmate.
- Mr. Simpson- Blinky's dog boss. He predates The Simpson cartoon.
- Gooey, Screwy and Ratatouille- A parody of Huey, Dewey and Louie and are Akbar and Jeff's triplet nephews.
Recurring Situations and Gags
- Fake Magazines
- How to Guides
- Miniseries- Strips told in a mock textbook-style
- Akbar & Jeff Discussing About Their Relationship
- Binky Tries to Meditate
- Ads for Akbar & Jeff's Shady Businesses
- Bongo Trapped In Detention
- Bongo Being Unhappy With The Huge Amounts of Gifts He Gets For Christmas
- Shadow Rabbit- Blinky's shadow towering over Bongo, when did something wrong despite his claims he didn't (even though it's obvious he did)
- How to Draw Blinky